|
The Open Source Drug Discovery
initiative would establish a novel open source platform for both
computational and experimental technologies to make drug discovery for
infectious/ neglected diseases, cost effective and affordable to the people
of the developing world. “Open-Source Drug Discovery” will be a program to
find cures for diseases that affect the world’s poorest of the poor.
OSDD will have independent biologists freely sharing their work through the
internet. As a first phase, drugs against Mycobacterium tuberculosis
including drug resistant and latent tuberculosis will be undertaken with
the following major objectives:
• Development of a web-based portal for data deposition, exchange,
evaluation and tabulation for analysis
• Collaborative sharing of know-how for the entire spectrum of processes in
drug discovery-- ranging from identification of drug-able nontoxic targets,
in vitro and in vivo validation, in-silico screening
of small molecules, lead optimization, pre-clinical toxicity and clinical
trials
• To create a comprehensive Systems Biology approach for drug discovery
• Human resource development with emphasis on encouraging young minds
• Intellectual property protection to the extent it supports public good -
One can apply for the Intellectual Property Rights, but these would be
shared among the open source community!
• Academia-industry partnership i.e., Public-Private Partnership (PPP) in
open source mode
• To establish an International Collaborative Centre for Affordable Health
(ICCAH), which will operate with Government, International and
Philanthropic funding.
|
|
|
|