Publications and Presentations - Open Source Drug Discovery (OSDD)

Publications and Presentations

Scientific Publications

Seal A, Passi A, Jaleel UCA, Wild D and OSDD Consortium; In-silico Predictive Mutagenicity Model Generation Using Supervised Learning Approaches, Journal of Cheminformatics, 15 May 2012, 4:10 doi:10.1186/1758-2946-4-10

Periwal V, Kishtapuram S, Open Source Drug Discovery Consortium, Scaria V; Computational models for in-vitro anti-tubercular activity ofmolecules based on high-throughput chemical biology screening datasets, BMC Pharmacology.2012 March 12:1 doi:10.1186/1471-2210-12-1

Singh H, Chauhan JS, Gromiha MM; Open Source Drug Discovery Consortium, Raghava GP. ccPDB: compilation and creation of data sets from Protein Data Bank. Nucleic Acids Res. 2012 Jan;40(Database issue):D486-9. Epub 2011 Dec 1. PubMed PMID: 22139939; PubMed Central PMCID: PMC3245168.

Periwal V, K.R Jinuraj, Open Source Drug Discovery Consortium, Jaleel UCA, Scaria V. Predictive models for anti-tubercular molecules using machine learning on high throughput biological screening data sets. BMC Research Notes. 2011 Nov 18;4(1):504. PubMed PMID: 22099929

Anand P, Sankaran S, Mukherjee S, Yeturu K, Laskowski R, Bhardwaj A, Bhagavat R; OSDD Consortium, Brahmachari SK, Chandra N. Structural Annotation of Mycobacterium tuberculosis Proteome. PLoS One. 2011;6(10):e27044. Epub 2011 Oct 31. PubMed PMID: 22073123; PubMed Central PMCID: PMC3205055.

Singla D, Anurag M, Dash D, Raghava GP. A web server for predicting inhibitors against bacterial target GlmU protein. BMC Pharmacol. 2011 Jul 6;11:5. PubMed PMID: 21733180; PubMed Central PMCID: PMC3146400.

Bhardwaj A, Scaria V, Raghava GP, Lynn AM, Chandra N, Banerjee S, Raghunandanan MV, Pandey V, Taneja B, Yadav J, Dash D, Bhattacharya J, Misra A, Kumar A, Ramachandran S, Thomas Z, Open Source Drug Discovery Consortium, Brahmachari SK. Open source drug discovery- A new paradigm of collaborative research in tuberculosis drug development. Tuberculosis (Edinb). 2011 Sep;91(5):479-86. Epub 2011 Jul 22. PubMed PMID: 21782516.

Maganti L, Das SK, Mascarenhas NM, Ghoshal N.Deciphering the Structural Requirements of Nucleoside Bisubstrate Analogues for Inhibition of MbtA in Mycobacterium tuberculosis: A FB-QSAR Study and Combinatorial Library Generation for Identifying Potential Hits. Molecular Informatics, October 2011, Volume 30, Issue 10, pages 863–872

Bhardwaj A, Scaria v, Patra D, Open Source Drug Discovery Consortium. Open source drug discovery: a global collaborative drug discovery model for tuberculosis. Science and culture, January-February, 2011, vol. 77, nos. 1–2, 22-26.

Bhat AG, Vashisht R, Chandra N. Modeling metabolic adjustment in Mycobacterium tuberculosis upon treatment with isoniazid. Syst Synth Biol. 2010 Dec;4(4):299-309. Epub 2011 Feb 26. PubMed PMID: 22132057; PubMed Central PMCID: PMC3065594.

Mishra NK, Agarwal S, Raghava GP. Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule. BMC Pharmacol. 2010 Jul 16;10:8. PubMed PMID: 20637097; PubMed Central PMCID: PMC2912882.

Mathew R, Kruthiventi AK, Prasad JV, Kumar SP, Srinu G, Chatterji D. Inhibition of mycobacterial growth by plumbagin derivatives. Chem Biol Drug Des. 2010 Jul;76(1):34-42. Epub 2010 May 4. PubMed PMID: 20456370.

Garg A, Tewari R, Raghava GP. KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials. BMC Bioinformatics. 2010 Mar 11;11:125. PubMed PMID: 20222969; PubMed Central PMCID: PMC2841597

Bhardwaj A, Bhartiya D, Kumar N; Open Source Drug Discovery Consortium, Scaria V. TBrowse: an integrative genomics map of Mycobacterium tuberculosis. Tuberculosis (Edinb). 2009 Sep;89(5):386-7. Epub 2009 Aug 14. PubMed PMID: 19683474.

Sharma S, Kumar M, Sharma S, Nargotra A, Koul S, Khan IA. Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis. J Antimicrob Chemother. 2010 Aug;65(8):1694-701. Epub 2010 Jun 4. PubMed PMID: 20525733.

Publications About OSDD

How Open Source Drug Discovery Is Helping India Develop New Drugs ; Seema Singh; Forbes India Magazine, April 9 2012
Samir Brahmachari - Fierce's Top 10 Biotech Techies; FierceBiotechIT , March 23 2012

Affordable Healthcare : the Open Source Way; Dr Sukanya Datta and Geetha Sugumaran; Emerging Science Vol 4 No 3, March 15 2012. Pg 40-43

India's "Science for All Academy ";Dr Ragunath Mashelkar, Science Vol 335; ,Feb 24 2012

India Rising : Crowd-Sourcing Drug Discovery ; Richard Stone with reporting by Pallava Bagla, Science Vol 335; ,Feb 24 2012

OSDD Chemistry OUTREACH Program (OSDDChem) : Current Science Correspondence, Dr Tushar Kanti Chakraborty,Nov 2011 101(10)

Hiroaki Kitano, Samik Ghosh & Yukiko Matsuoka. Social engineering for virtual 'big science' in systems biology. Nature Chemical Biology 7, 323–326 (2011) doi:10.1038/nchembio.574 Published online 17 May 2011.

Towards new business models for R&D for novel antibiotics. Drug Resist Updat. 2011 Apr;14(2):88-94. Epub 2011 Mar 25.

Geek Nation: How Indian Science Is Taking Over the World; Angela Saini , 2011 ; 288 pages.

Concise General Knowledge Manual; Edgar Thorpe, Showick thorpe , 2011.

Institute of Medicine: Extending the Spectrum of Precompetitive Collaboration in Oncology in Oncology research; Margie (CON) Patlak, Sharyl J. (CON) Nass, 2010; 112 pages.

B Munos. Can Open-Source Drug R&D Repower Pharmaceutical Innovation? Clinical Pharmacology & Therapeutics 87, 534-536 (May 2010) | doi:10.1038/ clpt.2010.26.

Incentives for Global Public Health: Patent Law and Access to Essential Medicines; Open Source drug discovery: a revolutionary paradigm or a Utopian model? Krishna Ravi Srinivas, 2010; 263 pages.

S&T Strategies of Six Countries: Implications for the United States; Committee on Global Science and Technology Strategies and Their Effect on U.S. National Security, National Research Council , 2010; 126 pages.

India: a reference annual; India. Ministry of Information and Broadcasting; 2010.

Institute of the Medicine of National Academics: The U.S. Commitment to Global Health. Institute of Medicine of the National Academics, 2009.

India Takes an Open Source Approach to Drug Discovery. Cell, Volume 133, Issue 2, 201-203, 18 April 2008

Science & Technology For Upscl; Singh, 2007; 36 pages.

Blogs About OSDD :

Paul. A ; A Spoonful of Open Innovation for Drug Discovery, April 10, 2012; Link http://www.ideaconnection.com/blog/tag/osdd/

Zunia,Open Source Drug Discovery (OSDD),March 02, 2012;Link http://zunia.org/post/open-source-drug-discovery-osdd/

Ashutosh ,Science in India: Moon shot or bust? March 1, 2012 ; Link http://www.criticaltwenties.in/sciencetechnology/science-in-india-moon-shot-or-bust

Geetha.S, OSDD-Redefining IPR in Open Source Innovations;December 7,2011;Link http://www.open-designism.com/profiles/blogs/osdd-redefining-ipr-in-open-source-innovations

Geetha.S, Garuda Grid - Helping Cross Computational Barricades;November 9,2011;Link http://scienceopenscience.blogspot.com/2011/11/04112011-further-strengthening-mou-was.html

Geetha.S;“Cloning and expression of selected intraphagosomal expressed genes of Mycobacterium tuberculosis” - OSDD Project at Miranda House; October 4,2011;Link :http://scienceopenscience.blogspot.com/2011/10/cloning-and-expression-of-selected.html

Jaimon Joseph, A Facebook for Labcoats; September 23,2011; Link :http://ibnlive.in.com/blogs/jaimonjoseph/326/62731/a-facebook-for-labcoats.html

The MedGuru, your Helath first; TB drug: Open Source Drug Discovery project attracts private firms; POSTED Fri, 04/15/2011; POSTED BY Varma.gbsnp; Link: http://www.themedguru.com/20110415/newsfeature/tb-drug-open-source-drug-discovery-project-attracts-private-firms-86144384.html

SPICY IP; Lawyers prevent the open access to TKDL, Versus OSDD; April 5, 2011; Link:http://spicyipindia.blogspot.com/2011/04/lawyers-prevent-open-access-to-tkdl.html

Access Health International, Open Source Collaboration in Drug Discovery By Anand Tatambhotla; Link:http://accessh.org/index.php/list-of-existing-blogs/233

WittySparks, OSDD at center of Bioinformatics, Kerala; November 12, 2010; Youtube video; Link:http://videos.wittysparks.com/id/495129840 Videos regarding OSDD:- http://hidilli.com/videos/?vq=osdd&k=1

Stem Cells. Regenerative Medicine; Posted by HemantVerma , Thursday, April 8, 2010; April 13, 2010 Links:-http://vermahemant.blogspot.com/2010/04/open-source-drug-discovery.html

NetworkWorld ; Can Open Source Defeat the Scourge of Tuberculosis? ; By Alan Shimel on Tue, 04/13/10 Link:http://www.networkworld.com/community/node/60022

A blog by Science journalist Angela Saini; Nothing Shocks me I’m a scientist; March 29, 2010; Link:http://angelasaini.blogspot.com/2010/03/hunt-for-new-tb-drug_29.html

PILMAN - A Tapan Ray Website; Open Source Drug Discovery (OSDD) initiative for the tropical diseases by CSIR and cancer by GlaxoS; Posted by Tapan Ray on December 3, 2009; Link: http://www.tapanray.in/profiles/blogs/open-source-drug-discovery

Technology Review published by MIT; Blog: 2,000 scientists join OSDD to tackle TB; Posted By: Narayanan Suresh; November 2009; Link:http://www.technologyreview.com/biomedicine/24029/page1/

SPICY IP; OSDD still well on track; Posted By Swaraj Paul Barooah; Monday, November 30, 2009; Link:http://spicyipindia.blogspot.com/2009/11/osdd-still-well-on-track.html

Center for Global Development; "The Best Thing to Come Out of India Since “Slumdog Millionaire”. Posted By Scott Kniaz; March 11, 2009 Link:- http://blogs.cgdev.org/globalhealth/2009/03/the-best-thing-to-come-out-of.php

BioSaga Blog; Open Source Drug Discovery Initiative, OSDD is a CSIR Team India Consortium with Global Partnership; Monday 12 January 2009; Link: http://lukeskywaran.blogspot.com/2009/01/open-source-drug-discovery-initiative.html

Bio Saga: Just another WordPress.com weblog; Creating awareness of extremely resistant TB; By jkwaran; YouTube link: http://www.youtube.com/v/yj8KZNI6-W8&hl=en&fs=1 Link:http://lukeskywaran.wordpress.com/2010/09/07/creating-awareness-of-extremely-resistant-tb-2/

SPICY IP; SPICY IP Interview with Dr. Samir K Brahmachari; March 19, 2008; Link:http://spicyipindia.blogspot.com/2008/03/spicy-ip-interview-with-dr-samir-k.html

Subpages (1): OSDD Newsletter

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24th March 2012-World TB Day Presskit and Pressrelease- pdf.zip

(7231k)

Anshu Bhardwaj,

Mar 23, 2012 1:04 AM

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CSIR_TBA_PressRelease .pdf

(407k)

Anshu Bhardwaj,

Mar 28, 2012 3:02 AM

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Foundation Day Lectures.pdf

(193k)

Anshu Bhardwaj,

Apr 16, 2012 10:54 PM

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OSDD brochure.pdf

(1291k)

Domain Administrator,

Jan 24, 2012 9:59 PM

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OSDD-Brochure-2012.pdf

(3389k)

Anshu Bhardwaj,

Feb 26, 2012 10:28 PM

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(4367k)

Domain Administrator,

Jan 24, 2012 9:58 PM

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OSDD_Update.pdf

(4176k)

Domain Administrator,

Jan 24, 2012 9:58 PM

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OSDD_slidesJan2012.pdf

(9932k)

Anshu Bhardwaj,

Feb 17, 2012 6:04 AM

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